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Several clinical studies have established beyond any possible doubt that the association is statistically much higher than could be expected by chance ( Table 18-5 )

Tau-mediated disruption of the spliceosome triggers cryptic RNA splicing and neurodegeneration in Alzheimers disease

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Membranes were probed using antibodies to FoxO1 (1:2500, 18592-1AP, Proteintech, Chicago, IL, USA), SOD2 (1:6000, 66474-1lg, Proteintech, Chicago, IL, USA), NOX4 (1:600, 14347-1-AP, Proteintech, Chicago, IL, USA), and -actin (1:2000, AM10218-400, Abgent) as the primary antibodies

Support for a Healthy Nervous System: Regular B12 supplementation helps maintain nerve health and can prevent complications related to prolonged deficiency