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Also, since the body is unable to metabolize the cocaine, large doses used cocaine addicts may easily cause overdoses and other unwanted side effects

Conclusion A series linear Ang IV analogues demonstrating improved metabolic stability and very high affinity to IRAP have been reported, e.g., the potent hexapeptides 11 (AL-11) and 12 (IVDE77) with Ki values of 7.6 and 1.7 nM, respectively, data to be compared with the Ki value of Ang IV of 62 nM in the same binding assay

Differential susceptibility of retinal neurons to the loss of mitochondrial biogenesis factor nrf1

3) proliferation