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Inhibition by p53 of GS-E transport by purified recombinant Rlip reconstituted in artificial liposomes supported the idea of mutually opposed functions of Rlip and p53, with the former acting to defend cells from apoptosis (in response to survivable stress) and the latter triggering suicide upon catastrophic stress

FIGURE 3 3.4 Preliminary conclusion: converging path to reproductive senescence Although environmental stressors may differ in origin, ranging from lifestyle factors to pollutants, they tend to converge on a limited number of shared pathophysiological mechanisms that drive reproductive aging

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The final 3D map has an average resolution of 3.6 at FSC = 0.143

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