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However, these studies were not followed by large-scale clinical trials which could unambiguously estimate whether thiamine should be given as a treatment for diabetic patients

The molecular mechanism of such an effect is based on the ability of glycine to initiate stable vasodilatation of arterioles, which has been demonstrated in rat pial vessels and in mesenteric arterioles [81, 82]

Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418

L., Garcia, A., Gillespie, C., Hukelmann, J

Chen and Nunez 2010