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doi: 10.1097/jom.0000000000001775 Summary Keywords exercise intensity, immune health, moderate-intensity exercise, immune cell function, cytokine regulation Citation Shi X, Hu L, Nieman DC, Li F, Chen P, Shi H and Shi Y (2025) Exercise workload: a key determinant of immune health a narrative review

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1 Introduction The liver is the largest solid organ in the human body and is responsible for critical functions such as metabolic regulation, detoxification, bile secretion and immune defence, playing a central role in maintaining homeostasis (Zaefarian et al., 2019)

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