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Indeed, VPA has fewer common side effects than do other AEDs, especially on behaviour and cognitive functions

78 This study was followed by a phase 2, randomized, double-blind trial enrolling 178 cirrhosis patients with history of recurrent HE who received either GPB (6 mL twice daily for 16 weeks) vs

15 - J.M

Nature 458 , 762765 (2009)

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Subsequently, the experiments were evaluated by measuring the amount of TMA released into the culture medium ( For the inhibition assay, 1,996 L of fecal slurry was placed in the wells of a deep-well plate, and 2 L of fermentation products solution diluted in sterile water was added at the beginning of the experiment (T0) to obtain a final concentration of 50 M (or 7.99 10 3 mg/mL)