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Biomarkers 17 , 671 (2012)

Indeed, the effects of efflux transporters such as p-glycoprotein can increase exposure of drugs to CYP3A enzymes in the intestine by prolonging transit time across the enterocyte (Wacher et al., 2001)

22 In vivo , CartIR / mice demonstrated alterations in growth plate development characterized by an increase in the overall numbers of chondrocytes and a reduction in size of cells in the hypertrophic zone

It can use intuitive mapping to assess the risk of individual patients

This may help explain the modest locomotor recovery observed in MSC-treated animals despite the limited graft survival (Ruzicka et al., 2017)

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