glutathione synthetase deficiency usmle Synthase - an overview 𧬠ππ²π£π ππ²π³πΆπ°πΆπ²π»π°π β ππΆπ΄π΅
X linked recessive NADPH RBCs can't handle oxidative stress NADPH keeps glutathione active protects RBCs Triggers ( Hemolytic Anemia Due to Gamma Glutamylcysteine Synthetase Deficiency: A Rare Novel Case in an Arab Muslim Israeli Child Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification Nineteen year follow up of a patient with severe glutathione synthetase deficiency Journal of Human Genetics A very common USMLE Step 2 CK trap macrocytic anemia in alcohol use, and many jump to the wrong deficiency. Chronic alcohol use + macrocytosis pancytopenia think folate Amino Acid Metabolism and Heritable Disorders of Degradation Cell Biology, Genetics, and Biochemistry for Pre Clinical Students
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