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When the local [Ca 2+ ] c rises, the uniporter that mitochondria use to take in Ca 2+ may act like a channel and remain open (Rizzuto et al., 2000)

Among the most important are the degeneration of dopaminergic neurons and the loss of the substantia nigra, combined with the intracellular aggregation of -synuclein, which forms Lewy bodies and neurites [7]

In the bowel, E

Treatment of pulmonary arterial hypertension: recent progress and a look to the future

6,335,167, 6,197,501, 5,830,645 and 5,665,549 and Albertson (1984) EMBO J.3: 1227-1234

[71]) was not affected by deletion of the meaB gene and strong nitrosative stress even downregulated it in both the wild type and the meaB strains (Fig