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Cells (5 10 4 ) were seeded into 24-well plates and grown until 95100% confluent

Frameshift insertion and deletion (indels), which are common in tumor cells, introduce novel open reading frames that produce aberrant proteins, known as neoantigens [124, 125]

2d,e) unlike GCLC or GSR, which exhibited no dependency ( Extended Data Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 208.Rodrigo-Gonzalo M.J., Gonzlez-Manzano S., Pablos-Hernndez M.C., Mndez-Snchez R., Ayuda Duran B., Gonzlez-Snchez J., Barbero-Iglesias F., Gonzlez-Params A.M., Recio-Rodrguez J.I