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Comparison of amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin for the treatment of diabetic peripheral neuropathic pain (OPTION-DM): a multicentre, double-blind, randomised crossover trial

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Godic A, Poljsak B, Adamic M, Dahmane R

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To expand on this limitation, one subject dropped out of the study and was unable to provide post-treatment scores at the end of the intended study period

This condition is often accompanied by mitochondrial dysfunction and elevated oxidative stress and can lead to disrupted menstrual regularity as well as reduced fertility potential in women trying to achieve pregnancy