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There are numerous risks to the body when glutathione stores are depleted

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Andreeff, M, Milella M, Konopleva M

In a two-generation study of reproductive toxicity in rats, the highest dose of 800 ppm (equivalent to 40 mg/kg bw per day) caused decreased body weights and food consumption in parental animals of each sex and decreased body weights in pups on days 7, 14, and 21 of lactation

Formation of Malonyl Coenzyme A in Rat Heart