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Except for orforglipron, incretin-based drugs appeared to increase HDL-cholesterol up to approximately 13% with pooled tirzepatide doses

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Eli Lilly reported these results in mid-2025, and the retatrutide availability timeline now points toward potential FDA approval no earlier than 2027, as additional phase 3 trials continue

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Then one morning you wake up with a face (or back, or chest) that looks like you're 16 again