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Abstract The increased incidence of inflammatory bowel disease (IBD) has become a global phenomenon that could be related to adoption of a Western life-style

Hence, curcumin suppresses cancer progression by inducing cell cycle arrest at various phases and promoting apoptosis through the modulation of key regulatory proteins, such as cyclins, CDKs, Bax, and Caspases

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While there are advancements in understanding risk factors and pathogenesis, challenges remain in the form of high variability in incidence rates, limited understanding of mechanisms, and the need for more effective management and preventive strategies