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Depression is accompanied by observation of oxidative DNA damage, namely 8-OH-Gua (see above) confirmed by the analysis of plasma, urine, and leucocytes of patients with depression (Black et al

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Magzoub RAM, Yassin AAA, Abdel-Rahim AM, Gubartallah EA, Miskam M, Saad B, Sabar S (2019) Photocatalytic detoxification of aflatoxins in Sudanese peanut oil using immobilized titanium dioxide

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The formation of new blood vessels is often insufficient to provide adequate oxygen to the synovium, leading to a decrease in local microenvironmental oxygen tension and the formation of a hypoxic synovial microenvironment, which in turn affects angiogenesis, inflammatory responses, matrix degradation, cartilage erosion, energy metabolism disorders, and oxidative stress (126, 127)