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Conversely, several inflammatory cytokines, such as prostaglandin E2 (PGE2), IL-1 and IL-6, have been confirmed to directly affect the onset of ferroptosis[87, 108, 109]

The 5-year prevalent cases, although a staggering figure of above 7 million for 2022, are very concerning from a socio-economic standpoint [3, 10]

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A study has constructed a PNMn hydrogel with multi-enzyme activities (POD, CAT, OXD) and excellent NIR-II photothermal performance

The high expression of copper-related genes, such as FDX1 and SLC31A1, in metabolic organs, such as the liver and intestine, poses a challenge in interpreting their specific roles in cardiovascular pathology, underscoring the need for tissue-specific models [263]