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Effects of hepatocytes on non-parenchymal cells Following liver injury, hepatocytes release various chemokines that attract immune cells to the site of damage, playing a key role in regulating the balance between injury and repair

Previous studies have shown that the absence of C-tail phosphorylation increases the flexibility of the linker between the SH3 and SH2 domains, known as an inducible snap lock, that may further enable the SH3 domain to accommodate not only extended polyproline sequences but also structurally diverse interaction partners 23

Ozempic, FDA-approved, is used for the treatment of type 2 diabetes and weight management

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Alidoost et al

(PubMed) Kunnumakkara AB, Anand P, Aggarwal BB