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3 Conclusion and Future Perspectives As phytotherapy, APS are appropriate for long-term therapeutic options in patients with chronic illness owing to relatively small toxic side effects, which has been the most difficult issue in the study of NAFLD treatments, resulting in a large number of medicines being abandoned in subsequent clinical trials

Exploring the neuroprotective role of HGF, different groups showed that HGF treatment of primary cerebellar granule neurons prevents apoptotic cell death through activation of the PI3K/AKT pathway signaling(Honda et al., 1995

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Final structure of sperm chromatin Histone-PRM exchange during the elongating phase of spermiogenesis modifies drastically the structure and spatial organization of sperm chromatin, which becomes 10 times more condensed than in somatic cells

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