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Glaucomatous rats presented with severe retinal damage and failed function were rats with permanent venous congestion and permanently increased intraocular pressure induced by cauterization of three of four episcleral veins (open-angle glaucoma model) [116,117,118,119,120,121]

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Mode of use of Difen B12 Injection: To prevent the possibility of a local irritant reaction that can be produced by the injection of concentrated solutions, it is essential to respect the following guidelines: - Perfect sterility of the instruments is required