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Interactions mediated primarily through the pre-NAC and NAC regions are more likely to inhibit aggregation, whereas interactions restricted to the terminiregions not part of the fibril coremay have little or no influence on Syn aggregation

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Together with enzymes like glutathione peroxidase (GPx) and glutathione reductase (GR), it plays a vital role in the body's antioxidant defense system, helping maintain cellular balance and protect against oxidative stress

The de novo synthesis of ERGO has been depicted in various fungi, including Basidiomycota [51,52]

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