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IV fluids typically remain in the body for 2 to 4 hours before being filtered by the kidneys and excreted as urine

Fitzpatrick MF, Engleman HM, Boellert F, McHardy R, Shapiro CM, Deary IJ, Douglas NJ (1992) Effect of therapeutic theophylline levels on the sleep quality and daytime cognitive performance of normal subjects

Melatonin, the primary hormone of the pineal gland, is a powerful chronobiotic that helps support a normal sleep-wake cycle.* Considerable evidence shows that melatonin levels peak during our "biological night" and are associated with the function of neurological, circadian and immune systems.*

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[49] [50] [51] Burnout prevention and balancing life [edit] After his personal experience with burnout at the peak of his medical career, Maroon developed a strong interest in burnout prevention and living a more balanced life

2004) and activated by light-dependent changes in the redox state of a cofactor (flavin) (Bouly et al