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Fabry disease patients present different phenotypes according to the mutation and the level of residual enzyme activity, pointing to the necessity of personalized disease modeling

Reduced gastrointestinal absorption and increased utilization during acute stress states exacerbate this deficiency

Antilipogenesis (the inhibition of fat accumulation) is mechanistically distinct from lipolysis (the active mobilization of existing fat stores)

In the small intestine there are invaginations called crypts of Lieberkuhn and prominences into the lumen called villi with differentiated cells

Hashimotos thyroiditis (HT) is an organ-specific autoimmune disease that disrupts thyroid hormone production and typically progresses to hypothyroidism, defined by the presence of serum anti-thyroglobulin (TgAb) and anti-thyroid peroxidase (TPOAb) antibodies directed against thyroid cells (Waliszewska-Pros And Ejma 2022)