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Description

PMID: 19180561

MOTS-C works by activating the AMP-activated protein kinase (AMPK) pathway, a central energy-sensing mechanism that promotes glucose uptake, fatty acid oxidation, and insulin sensitivity

They are listed here as a reference for researchers investigating 5-Amino-1MQ

This medicine is used to treat vitamin B12 deficiency caused by poor absorption, including pernicious anemia and certain stomach, intestinal, or surgical conditions

In studies with mouse models of NAFLD and acute kidney injury (AKI), treatment with ACMSD inhibitors increased the transcription of mitochondrial and -oxidation genes, as well as restoring NAD + levels in the kidney and liver 235