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5F, G), demonstrating that Alpi+ enterocyte-derived cells had reacquired Lgr5 expression and occupied the CBC niche

Thiazolidinediones are insulin sensitizers that function mostly through increasing insulin sensitivity in target organs such as the liver and muscles ( 3.1.1 Mode of action The activation of a transcription factor, peroxisome proliferator-activated receptor (PPAR), is the mechanism by which TZDs exert their anti-diabetic action

The prevailing opinion is that they pose no threat to human health or, at most, a negligible risk

DNA synthesis Essential for normal cell division 4

In severe cases, hyperammonemia has been known to cause brain damage and even death

Patient-derived glial enriched progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents