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The concern stems from its activation of the VEGFR2 pathway and FAK-paxillin signaling, which drive angiogenesis and are dysregulated in 50% of human cancers (ovarian cancer, melanoma, and colon adenocarcinoma)

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Ebrahimnejad, P., Taleghani, A

Bertran-Alamillo J, Cattan V, Schoumacher M, Codony-Servat J, Gimnez-Capitn A, Cantero F, et al

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