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Although the liver is also the principal source of circulating IGFBP-3 and ALS, other tissues have been proposed to produce these factors[48, 49]

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Nat Genet 2013

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Collectively, our study demonstrates that engineered bispecific antibodies targeting drug-modified KRAS G12C neoantigens enhance MHC presentation and elicit potent, selective T cell-mediated cytotoxicity across HLA supertypes