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However, preclinical and clinical investigations performed in order to investigate the utility of this combinatory drug strategy in cancer (i.e., HMGCR inhibitors plus SREBP inhibitors), are still a pharmacological challenge

Debate cardiovascular : Un estudio de 2013 relacion el consumo elevado de L-carnitina con el aumento de los niveles de TMAO (trimetilamina N-xido), lo que puede aumentar el riesgo de cardiopatas en algunas personas

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They primarily act as catalysts for enzyme actions while some metallic ions take part in oxidation-reduction reactions involved in energy metabolism [2]

Molecular basis of the anti-aging' effect of spermidine and other natural polyamines - a mini-review

While current clinical and basic evidence strongly supports ferroptosis as a key contributing mechanism in periodontitis progression, the extent of its role relative to classical pathogenic factors such as dysbiosis and immune dysregulation, as well as its causal temporality in the natural history of the disease, remains unclear