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In addition to conventional covalent warheads that directly form covalent bonds with amino acids, small molecules may also break bonds while forming new bonds

Typically, for estimation of Hcy by HPLC in plasma/serum or tissue homogenates, the samples are subjected to a reduction reaction using reagents like tri-n-butylphosphine that renders the SH/thiol group free

48 It is further believed that fungal fermentation produce more antioxidants than those produced by bacterial fermentation

Protein oxidation is another critical mechanism where free radicals modify amino acid side chains, form protein-protein cross-links, and fragment peptide chains

Parenterally administered dipeptide alanyl-glutamine prevents worsening of insulin sensitivity in multiple-trauma patients