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Consequently, due to its apoplastic localization, AsA constitutes a vital role in stress perception, redox homeostasis and subsequent regulation of oxidative stress and plant physio-biochemical responses under normal as well as different abiotic stresses

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In addition, the mode of action of gabapentinoids has been suggested to involve inhibition of descending serotonergic facilitation, stimulation of descending inhibition, anti-inflammatory actions, and influence on the affective component of pain [23]

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doi:10.1016/0304-3940(90)90586-X 92

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