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coli BL21 Codon-Plus competent cells (New England Biolabs) and grown at 37 C in 2% Luria Broth containing 0.2% glucose and 100 mg/L ampicillin until OD 600 reached 0.30.37, at which point protein expression was induced with addition of 0.4 mM isopropyl -D-1-thiogalactopyranoside (IPTG)

Once mixed, the sermorelin solution should be stored in the refrigerator (between 36F and 46F)

BCL-2 antagonist ABT-199 combined with complex I inhibitor IACS-010759 blocks mitochondrial respiration and facilitates anti-leukemia effect in pre-clinical AML models