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Autopsy revealed decreased plasma GSH levels (Klepac et al

Mitochondrial cytochrome P450 enzymes, embedded in the IMM with most of their protein body facing the matrix, bind a single heme moiety 88,89

It suggested a non-linear dose-response relationship, indicating that a daily intake of 2000 mg (oral) of L-Carnitine could provide the maximum effect in reducing body weight among adults, particularly those with overweight or obesity