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DeMaio, A., Mehrotra, S., Sambamurti, K

David further analyzed 71 target genes, the prediction of biological processes (BP), including protein phosphorylation (GO:0006468), positive regulation of cell proliferation (GO:0008284), peptidyl-serine phosphorylation (GO:0018105), Positive regulation of gene expression (GO:0010628), negative regulation of apoptotic process (GO:0043066), response to lipopolysaccharide (GO:0032496), positive regulation of MAPK cascade (GO:0043410), positive regulation of MAP kinase activity (GO:0043406) (Figure 11D)

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A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults

Combining the easy scale-up of the DEF-CS single-cell culture system for iPSCs, the highly efficient DE induction by the STEMdiff Definitive Endoderm kit, the robust hepatic specification guided by DMSO and HGF, and the hepatocyte maturation promoted by DEX, dihexa and OSM, this improved method may allow for robust generation of homogeneous functional hepatocytes from human stem cells and opens up new possibilities for drug discovery, hepatotoxicity studies and liver regenerative therapy