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Together, these peptides act on core hallmarks of aging: inflammation, oxidative stress, mitochondrial decline, and extracellular matrix degradation

GSH is used to repair oxidative damage, support immune function, and detoxify pollutants, heavy metals, and drugs

10 , 5158 (2018) R.M

For instance, porphyrin units can coordinate with metal ions like Cu 2+ to mimic the activities of catalase (CAT) and glutathione peroxidase (GPx), helping to modulate the immunosuppressive tumor microenvironment (TME) (155)

Additionally, Fe 3+ can be reduced to Fe 2+ via oxidizing GSH, accompanying the production of OH through a Fenton-like reaction

[Google Scholar] 9.Biological activities and potential oral applications of N-acetylcysteine: progress and prospects