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Genetics 225 , iyad147 (2023)

coli MG4 pKDT17 (Addgene, Watertown, MA, United States, 27503) was used in crossfeeding assays with the wild-type, pmtA or pmtA:pmtA PAO1 strains and E

As research continues to unravel the intricate mechanisms of this bidirectional communication, it becomes increasingly clear that targeting the braingut axis holds significant potential for advancing the treatment of both gastrointestinal and neuropsychiatric disorders, ultimately bridging the gap between physical and mental health

p53 promotes CDKN1A gene transcription (coding for p21), which is known for regulating the cell cycle (134,135)

Through these substances, the immune system may signal to the brain and interact with other factors involved in sleep regulation such as neurotransmitters (acetylcholine, dopamine, serotonin, norepinephrine, and histamine), neuropeptides (orexin), nucleosides (adenosine), the hormone melatonin, and the hypothalamus-pituitary axis (HPA) axis