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Cystathionine beta-synthase (CBS) contributes to advanced ovarian cancer progression and drug resistance

siRNA knockdown validation by qRTPCR For siRNA knockdown validation by qRTPCR, senescent and non-senescent SK-MEL-103 cells were generated as described before

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In vitro , apigenin inhibits LPS-stimulated maturation and chemotaxis of bone marrow-derived dendritic cells (BMDC) by inhibiting the expression of costimulatory molecules (CXCR4 and CCR7) and MHCII and reducing the secretion of cytokines (TNF-a, IL-12p70 and IL-10)