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In Cohort 1, 25 WT and 25 RAMP1/3 KO male mice aged 1220 weeks old were injected intraperitoneally after a 12-hour fast with vehicle, sCT at doses of 3 or 150 nmol/kg, or Cagrilintide at a dose of3 nmol/kg

PubMed For laboratory and research use only

These careful steps keep each peptide pure, stable, and dependable for consistent research outcomes

The formation of ice crystals can physically damage the peptide structures

doi: 10.1007/s00775-009-0600-y

Modified physicochemical properties the C-terminal amide changes the overall charge distribution of the molecule slightly, which can affect solubility and how it interacts with biological matrices