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doi: 10.1016/j.stemcr.2019.05.027 6 SuiBDHuCHZhengCXJinY

J Funct Foods 66:103831 Heinrich UR, Fischer I, Brieger J, Rmelin A, Schmidtmann I, Li H, Mann WJ, Helling K (2008) Ascorbic acid reduces noise-induced nitric oxide production in the guinea pig ear

UV radiation exposure indirectly initiates MMP activation without upregulating collagen production, causing decreased collagen levels and ECM fragmentation (72)

Moving release farther down the intestinal tract changes the pH, enzymes, transit conditions, mucus layer, surface area, and local concentration around the formulation

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They should be only used in analytical applications if the ligand is quite stable or in preparative applications if both the ligand and target are relatively stable and it is enable to recover their activity after such elution [8,23]