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as the Site Management Organization for the clinical trial

Rosas, H

2018 Dec;59(10):1174-1180

HIF-1 can activate PDK1 (phosphatidylinositol-dependent protein kinase 1), which can then phosphorylate and inhibit pyruvate dehydrogenase (PDH) E1[130], thus inhibiting acetyl coenzyme A synthesis, and blocking the TCA cycle and thereby freeing pyruvate from mitochondrial OXPHOS

doi: 10.1007/s00405-020-06290-3 16 DingB.WaltonJ

Comparative of functional metabolomics and transcript analyses were conducted in Chinese cabbage grown on half-strength MS solid medium with different Cd concentrations (5, 25, 100 M Cd)