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Treatment with the iron-chelating agent Downstream Facing Port (DFP) in the EAE model has shown promising results, reducing Transferrin receptor protein 1 (TfR1) content, reversing iron overload, and inhibiting demyelination

Atherosclerosis 289, 176178

The research clearly shows the positive effects of folates on the placenta during early gestation

To overcome challenges such as biosafety, off-target effects, and clinical translatability, strategies successfully explored in other diseases, such as biodegradable or organicinorganic hybrid nanozymes, pH-responsive targeting designs, erythrocyte membrane coatings, and ROS-responsive carriers, may be adapted to enhance tissue specificity and safety in IMID treatment

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