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A.PoloA.et al (2021)

2025 Apr 22;16(1):3777

Wu J, Li X, Huang H, Xia X, Zhang M, Fang X

RRM2 also facilitates immune escape through the promotion of macrophage infiltration and polarization in lung cancer cells [149]

In neuroinflammatory conditions, heightened ROS production induces deleterious effects on mitochondrial respiration and OXPHOS, leading to DNA oxidation, rearrangements and mutations (43)