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An important consideration is balancing the mechanics of these scaffolds with their resorption and ability to form new cartilage tissue

They have patterns of damage across multiple joints and soft tissue areas that a single injection site cannot address

Early signs include limited eye contact, delayed speech, and unusual responses to sensory input

The diagnostic value of holo-TC has proven superior to Hcy and MMA for the assessment of vitamin B 12 status in the elderly (Valente et al., 2011)