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You should arrange a consultation with your GP or endocrinologist before starting any weight management medication to discuss your individual circumstances, review your thyroid function, and determine whether this approach is appropriate for you

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From an athletes perspective, I also wont consider using it until it has been approved by anti-doping authorities

Liu, C., Zhao, W., Gao, X., Wang, N., Lv, Y., Ning, Z., & Sun, J

This can reflect the downstream effects of chronic microglial activation and dysregulated blood-brain barrier permeability

2019 Jan;34(1):157) Piccinin E, Sardanelli A, Seibel P, Moschetta A, Cocco T, Villani G (2021) PGC-1s in the Spotlight with Parkinsons Disease