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LPS binds to its binding protein to form the complex and is recognized by TLR4 on the surface of immune cells, followed by neutrophil infiltration and the accumulation of inflammatory factors (TNF-, IL-1, IL-27, etc.), which increases the risk of atherosclerosis [297, 298]

40 referencing the prior work by Rad et al

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Of note, the strongest fluorescence was observed in the GCMR group, suggesting enhanced OH production which is attributed to the further depletion of GSH by outer MnO 2 , as mentioned above (Figure 3C)