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Cell Proliferation/Viability Assay WB WB WB WB All MEK Isoforms More Biological Activity 50 & Target [1] In Vitro In BRAF mutant SK-MEL-28 cells and KRAS mutant HCT116 cells, Trametinib (GSK1120212;JTP-74057) DMSO solvate causes dose-dependent inhibition of ERK1/2 phosphorylation as well as dose-dependent growth inhibition

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10.1007/s11255-011-9969-y Int Urol Nephrol

Near normalization of metabolic and functional features of the central nervous system in type 1 diabetic patients with end-stage renal disease after kidney-pancreas transplantation

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