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[5] Neuromodulator [edit] GSSG, along with glutathione and S -nitrosoglutathione (GSNO), have been found to bind to the glutamate recognition site of the NMDA and AMPA receptors (via their -glutamyl moieties), and may be endogenous neuromodulators

PubChem Reference: View compound profile on NIH PubChem Key Characteristics MOLECULAR PROFILE Formula: C 62 H 98 N 16 O 22 Weight: 1,419.53 g/mol CAS: 137525-51-0 Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val PHYSICAL PROPERTIES Form: White to off-white lyophilized powder Solubility: Readily dissolves in water Stability: Stable across various pH conditions Storage: Keep refrigerated 3646 F (28 C) Related products MOTS-c $60.00 $190.00Price range: $60.00 through $190.00 TB-500 $60.00 $90.00Price range: $60.00 through $90.00

Oxidative stress has been researched to contribute significantly to mild cognitive impairment (MCI), characterised by low confidence in executing daily activities, repeating a certain phrase or question, and losing pleasure in daily activities and relationships

This dose increased oxidative stress, disrupted lipid metabolism, and suppressed ATP production

First-in-man tau vaccine targeting structural determinants essential for pathological tau-tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer's disease model

Animals were treated with DOX (8 mg/kg) once per week for 4 weeks, with ultrasound imaging every week to assess parameters of ( A ) left ventricular structure and ( B ) cardiac function