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Several studies have shown that most patients with severe COVID-19 exhibit markedly increased concentrations of pro-inflammatory cytokines in their serum, including IFN-, IFN-, IL-1, IL-6, IL-12, IL-17, IL-18, IL-33, TNF-, G-CSF, GM-CSF, IP10, MCP1, MIP1, and C-reactive protein (CRP) [68, 69], suggesting a combination of the pre-existing pro-inflammatory status observed in older individuals with an additional virus-induced pro-inflammatory status

Jackson wrote that she woke barely able to lift her neck, then developed tingling and numbness in her hands until she could no longer squeeze the brakes safely on steep descents