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The subcutaneous route is generally considered the preferred method for administering peptides such as insulin-like growth factor 1 because it provides slower release and increased half-life of the medication compared to injecting them intramuscularly

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In some species, GH acts directly on androgen action, thereby accelerating the pubertal transition, because GH reduces the amount of testosterone required to induce secondary sexual characteristics (axillary hair) in young individuals [25]

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