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J Reprod Infertil 2018

A study has demonstrated that homozygous deletions in CPT1B are lethal in mouse (Ji et al., 2008)

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In this case, miRNAs can alter the gene expression of the CPT2 and CPT1 genes, which in turn affect mitochondrial function and fatty acid oxidation.[ref] Similarly, supplemental L-carnitine can affect inflammatory pathways through altering the expression of microRNAs that in turn decrease inflammatory cytokines.[ref] Genotype report: Carnitine Access this content: An active subscription is required to access this content

(31), where higher L-carnitine concentrations in the medium inhibited -butyrobetaine hydroxylase activity but left -N-trimethyllysine hydroxylase activity unaffected