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This can occur due to loss of appetite, digestive issues, and muscle weakness, which are common side effects of B12 deficiency

Contraindications/Precautions Cyanocobalamin is contraindicated in those with hypersensitivity to cobalt moiety or cobalamin molecule due to the risk of anaphylaxis (9)

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Only a confirmed deficiency should lead to a prescription for B12 injections

Another study conducted by the University of California found that B12 supplements improved energy levels and reduced fatigue in individuals with chronic fatigue syndrome

served as site principal investigator for the clinical trial (he received no financial compensation, nor was there a financial relationship) and reports advisory/consulting fees and/or other support from Boehringer Ingelheim, Eli Lilly & Company, Guidotti Laboratories, Menarini Diagnostics, Novo Nordisk and Therascience Lignaform