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In the liver tissue of the model group, the expression of TGF-1 and phosphorylated Smad3 significantly increased, whereas the expression of Smad7 decreased

Abnormal iron metabolism may cause iron accumulation in various tissues, including the brain, liver and pancreas, potentially inducing neurodegenerative changes such as neuronal loss, gliosis and mitochondrial dysfunction, which may clinically manifest as ataxia, dystonia and dementia (23)

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I cant prove that, but I think its very interesting to think about for those two exercises